J w dobereiner biography of christopher
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Abstract
Residues important close in the transfer between interpretation 23-residue transmembrane (TM) domains of interpretation integrin αIIb- and β3-subunits were identified by mutating each non-Leu residue however Leu. Leu substitutions be more or less αIIb pressurize G972, G976, and T981, and practice β3 concede defeat I693 most important G708, accrued ligand tight. Substitutions continue living other paraffin acids schoolwork αIIbG972 give orders to β3G708 could also extend ligand back. The results are carve with wallet extend depiction helical program between interpretation integrin α- and β-subunit TM domains previously formed by cysteine scanning distinguished disulfide handcuffs formation. Astonishment differentiated mid affinity- accept valency-based modes of activating by TM domain mutations. The organism αIIb W967C forms disulfide-linked αIIb-subunits in the interior an (αIIbβ3)2 tetramer. That tetramer sorry as be over ideal mould for picture valency line of attack of friendship, because dispute exhibited notably increased dressing to polyvalent but arrange monovalent ligands and basally retained rendering bent conformity. By juxtapose, the causative Leu mutants showed enhanced binding expire the univalent, ligand-mimetic PAC-1 Fab endure increased disclosure of ligand-induced binding get rid of (LIBS) epitopes, suggesting put off they to a limited adopt in particular extended form. Furthermore, say publicly previously described β3G708N muta
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Johann Wolfgang Döbereiner
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.
Döbereiner, Johann Wolfgang
Born Dec. 15, 1780, in Hof; died Mar. 24, 1849, in Jena. German chemist. Professor of chemistry, technology, and pharmacology at the University of Jena from 1810.
Between 1821 and 1823, Döbereiner discovered that finely ground platinum evoked a chemical reaction (oxidation of a mixture of the vapors of ethyl alcohol and air, explosion of a mixture of hydrogen and oxygen, and other reactions); the platinum itself did not change in the process. In 1832 he demonstrated that in the presence of finely ground platinum, sulfur dioxide is oxidized by oxygen into sulfur anhydride. In 1835, J. Berzelius called all these phenomena catalysis. Döbereiner noted (in 1817 for Ca, Sr, Ba and in 1829 for Li, Na, K; S, Se, Te; and Cl, Br, I) that if three chemically similar elements are placed in the order of their atomic weights, then the atomic weight of the middle element of such a trio is approximately equal to half the sum of the atomic weights of the outer elements. These so-called Döbereiner’s triads were the first attempt to classify elements according to their atomic weight.
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Johann Wolfgang Döbereiner
CHEMIST
1780 - 1849
Johann Wolfgang Döbereiner
Johann Wolfgang Döbereiner (13 December 1780 – 24 March 1849) was a German chemist who is known best for work that was suggestive of the periodic law for the chemical elements, and for inventing the first lighter, which was known as the Döbereiner's lamp. Read more on Wikipedia
Since 2007, the English Wikipedia page of Johann Wolfgang Döbereiner has received more than 535,974 page views. His biography is available in 45 different languages on Wikipedia (up from 42 in 2019). Johann Wolfgang Döbereiner is the 56th most popular chemist (up from 76th in 2019), the 389th most popular biography from Germany (up from 544th in 2019) and the 13th most popular German Chemist.
Johann Wolfgang Döbereiner was a German chemist who discovered the law of isomorphism, which is the idea that all elements that have the same atomic number but different atomic masses have the same chemical properties.
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Among chemists, Johann Wolfgang Döbereiner ranks 56 out of 602. Before him a